HIV Vaccines Essay Example for Free

HIV Vaccines Essay A vaccine is a biological preparation intended to improve an individual’s immunity to a specific illness or disease. Most vaccines are composed of weakened or killed forms of an agent that resembles a disease-causing microorganism. A typically safe version of the pathogen, which is unable to cause the disease, is then produced by the altered or inactivated state. Once the vaccine is administered into the blood stream, the agent is recognized as a foreign body, which then triggers the process of active immunity, which in turn builds up antibodies to fight this particular pathogen (Wisegeek). Vaccination is intended to provide protection so that if the body comes in contact with the same type of disease in the future, the immune system will already have memory antibodies to fight the disease before symptoms occur. Since the introduction of vaccines for illness causing pathogens, diseases such as measles, polio and the common flu have greatly decreased in occurrence. With that being said, not all vaccines have been proven to be safe or effective. One virus that does not yet have an effective preventative vaccine is the Human Immunodeficiency Virus (HIV). HIV is a retrovirus that attacks the human immune system. Transmission of the virus can occur in many different ways; through contact of infected secretions of one person with the genital, oral, or rectal mucous membranes of another person. HIV can also be transmitted through blood and from mother to child during pregnancy, childbirth or through breast milk (Healthmagic, 2010). The virus is characterized by its two glycoproteins: gp120 and gp41. The larger of the two glycoroteins is gp120, this molecule is the primary site of attachment to CD4 receptors of the host cell and while also triggering inflammation when shed into the blood. Gp41 promotes fusion to a target cell while remaining on the cytoplasmic membrane. HIV infects four types of cells: helper T cells, macrophages, smooth muscle cells and dendritic cells. Attachment and entry of HIV into T cells and macrophages occurs in three steps. In the first step, gp120 binds to the CD4 (cluster of differentiation 4) molecules on a host cell; forming a complex known as gp120-CD4 complex. Second, this complex binds to a chemokine receptor, which removes gp120 from the virion. This process if finalized when the virion binds to a cell. Once bound to a cell, the virion’s envelope contacts and fuses with the cytoplasmic reticulum through the medium of the gp41. The HIV capsid then gets insinuated into the cytoplasm; however its covering of gp41 gets left behind and becomes part of the cells cytoplasmic membrane. With gp41 remaining on the cytoplasmic membrane, it is then able to fuse with over 500 cells to form a syncytium, which is a giant cell with multiple nuclei. This fusion is very dangerous because it allows HIV to move from cell to cell without being exposed to any antibodies that are in the blood. During synthesis, an enzyme called reverse transcriptase, transcribes the double stranded DNA using TRNA as a primer in the cytoplasm. Reverse transcriptase is prone to making a lot of errors during this process which generates an abundance of new antigenic variations of HIV. The double stranded DNA then enters the nucleus and is inserted into a chromosome by the enzyme integrase. Once the double stranded DNA is integrated into the cellular DNA it remains a part of it for life. Once the newly infected double stranded DNA is integrated into the chromosome, it cannot be changed or counter acted. However, there are various therapeutic vaccines to help regulate the virus (Bauman, 2011). Therapeutic vaccines are designed to help treat people who are HIV positive by controlling the virus. Those who are infected with HIV and live with it for an extended period of time, start to develop antibodies on a specific part of the glycoprotein 120, which is in charge of initiating the activation of HIV. This antibody, C5, is known to be crucial in producing certain antibodies that are able to control HIV by regulating its hyper action that destroys the human immune system. However, induction of these antibodies cannot occur unless GP120 is at the surface of the virus. In order for gp120 to be at the surface of the virus, gp41 and the antibody C5 must fuse. This is a process that is unable to occur on its own (Bionor Pharma, 2010). The therapeutic vaccine Vacc-C5, invented by Bionor Immuno, is an antibody-mediated vaccine that binds C5 and gp41 together so that the antibodies from C5 can be effective and help regulate the virus. A preventative vaccine is designed to prevent individuals from getting HIV. Over the recent years there have been many studies and attempts to create an effective vaccine to prevent HIV but unfortunately none have been proven to be successful. A good example of a preventative vaccine, that had hopeful prospects, is the AIDSVAX vaccine developed by Philip Berman. AIDSVAX is composed of a synthetic version of the glycoprotein 120, a part of the HIV’s envelope, which the virus uses as a mechanism to latch onto and enter the cell. This version of gp120 was meant to stimulate the production of antibodies against strains of HIV that it resembles, giving immunity to the strain of HIV. However, this vaccine was proven ineffective after the clinical trials. Near the part of the gp120 that attaches to the cell, there is a chain of a specific sequence of amino acids called the V3loop. The V3loop is the most variable part of the glycoprotein and in order for an envelope vaccine to produce an antibody response; it has to be against the exact strain of the virus (Brian Deer). HIV is a virus that has many different strains and is also constantly going under mutations within replication therefore preventing the AIDSVAX vaccine from halting the infection of the virus. The development of vaccines against HIV has not yet reached a point of success. HIV is a virus that has many characteristics that make it highly difficult to prevent and treat. HIV is capable surpassing immune response because of its ability of generating many antigenic variants; due to it being so highly mutable. Also, not only does HIV attack the various cells in the body that combat infections in the immune system but it can also spread through syncytia via formation by gp41, evading detection from immune defence all together. Vaccine development is still an important tool in healthcare because there are still millions of people who currently live with the disease and many who are at a high risk of contracting it. However, even with the many developments in medical research, the production of vaccines is still a costly procedure which also presents ethical and medical problems. In the meantime, the spread of infection must be slowed through the increase of awareness and availability, of information on the risks of contracting the disease. In order to avoid contraction, Health Care Providers must provide the public with information about safer practices, such as; safe sex and the proper use of sterile needles and syringes for injections. They can also promote proper blood screening procedures and spread information on medications, therapeutic vaccines and other ways an individual who already has HIV can prevent the spread of the virus as well.

Cool Hand Luke :: essays research papers

In Cool Hand Luke, the movie begins with the word, VIOLATION, across the screen. The word is from a parking meter and sets the tone for the entire movie. Luke Jackson, the title character, is arrested for cutting off the heads of the town’s parking meters while drunk, or in legal terms, for destroying municipal property while under the influence of alcohol. When asked why he cut the heads off the parking meters, Luke answers, â€Å"You could say I was settling an old score.† While it leaves the viewers believing that he probably received a parking ticket at some time in the past, no clues are given to what the old score may have been. He is sentenced to two years in a road prison, in a chain gang. His punishment did not fit the crime, and today, such an act would probably result in time spent in community service rather than a hard labor prison gang. To further accentuate that his sentence is worse than his crime, Luke Jackson dies at the end of his story. Luke is a decorated veteran, yet left the military service just as he went in, as a Private. This indicates that he had authority problems while there. He received the Silver Star, Bronze Star and a couple of Purple Hearts and that indicates that he is brave and probably humanitarian, because the Silver Star is usually given in recognition of a life-saving deed of valor. That he was never promoted, or else promoted and consequently demoted, (the story does not elaborate on the details) indicates that his superiors, those who had the authority to promote him, did not react well to his achievements. For Luke, death represents ultimate freedom. There is no doubt that he believes in God, in that he talks to God several times throughout the movie, yet his conversations are always more like arguments than prayers. In one of the final scenes, the empty shell of a church represents Luke’s relationship with God, and even the emptiness in himself. Luke feels that God has never been there for him. He tells God just before the end of the story that God hasn’t ever dealt him a good hand. That military authorities considered him a hero, decorating him with medals, doesn’t make him a hero in his own eyes. Luke is a tortured soul, in that he tells God that he doesn’t deserve any good thing because he killed people in the war. Still, Luke is a free spirit, true to himself, with no regard for the rules and regulations of other human beings. The crime he is arrested for is not one of violence toward any person, it is

Aditya Birla Case notes

The Unknown Global Indian Conglomerate Q) After a decade of reform, had the Barilla group done enough to outpace its rivals , or was there another step It had to take to be â€Å"Barilla #1†? NAS: Once Kumar Mangle Barilla took over the Barilla group in 1995 after the untimely death of his father, he ushered In an era of reforms and mandated the company be among the top three players In the world or at least in the region for any particular Investment. The renewed focus of the group was in making investments in India, acquiring companies outside India fuelling growth.One of his notable acquisition was Novels to make the high-risk aluminum business less vulnerable to price fluctuations on the London Metal Exchange. (Novels was acquired by Handball). Mangle Barilla focused on strengthening and consolidating similar businesses together and investing in growth business sectors from the cash generated from the value businesses. His strategy paid off and from being a conglomerate wi th Just US$I . 5 billion in revenues in 1995 it had grown to a business with revenues of approximately US$40 billion in year 2012.Though the group has come a long way It Is still at number three amongst the Indian Conglomerates(Number 1 being Data with revenues of US$OHIO billion as of 2012 and RILL with revenues of US$74 billion). In certain businesses the group Is number one Like VS. and cement whereas In certain other sectors like retail It needs to work towards establishing itself amongst the top three. The level of competition has increased both at home and abroad and the Barilla group needs to rethink their strategy to be the number one. The Barilla Financial services can play a major role with insurance company and an asset management fund.As a conglomerate it should be able to reap the benefits of distributing its costs across similar businesses and achieve cost leadership to gain a competitive advantage over its rivals. The group is looking at investment opportunities in Af rica, South America, East Europe and Central Asia because these geographies present Immense opportunities for the group to do business. The next logical decision of the group would be to Invest in Infrastructure and the group Is actively seeking out opportunities for the same. With the new government In place this might be one of the lucrative business opportunities.The roof is diversified across many sectors but it should be cautious enough not to spread its wings too thin. Recently the group sold off Ditty Barilla Maniacs as the group wanted to exit the business process outsourcing sector because it lacked scale and was not amongst the top three players in the particular region. The capital raised from the deal was invested in other growth sector opportunities in the group. The group has redefined its business strategy and management practices aimed at becoming the foremost firm in India but it still has a long way to go. According to Kumar Mangle Barilla he has all the large piec es in place.

Content Of Professional Ethics For Accountants Accounting Essay

IntroductionCode of professional behavior for comptrollers, is the basic content of professional moralss for comptrollers, which the comptrollers should follow in the business activity and is used to set the behaviour of comptrollers. Along with the economic development, the behaviour criterions, the working types and the societal environment has had the alteration mostly. Meanwhile, people ‘s political orientation and value is besides altering. And the codification of moralss for professional comptrollers to breed ethical behaviour is uneffective. Lovell ( 1995 ) said: Much unfavorable judgment has been arisen at the accounting profession, such as the failure of accounting paperss and the failure of the accounting profession satisfactorily to take history of the public involvement in the finding of the hereafter of accounting and scrutinizing pattern. Many jobs have risen, such as, accounting information untruthful, accounting action ‘s nonstandard. It disarrangesA the o rder of the accounting profession. So observers have questioned the effectivity of the codification. In this article, it will discourse why the codification of professional behavior for comptrollers is uneffective. It refers five facets that are of import.BodyThere are defect and cleft bing in the system building. Related jurisprudence and codification of comptrollers are non perfect, and the system is imperfect, which carries out it can be suiting and is really easy to take advantage. Some accountant ordinances system is disused, does non accommodate with the present economic work activity, and needs to revise. Harmonizing to Reiter ( 1997 ) , there should be new paradigms for accounting pattern, in order to breed ethical behaviour of comptroller. Besides there are many sorts of accounting codification at the same clip, which affected the behaviour of members of the accounting profession. Accounting Furthermore accountant the object locates the environment of accounting is complica ted and diversified, which carries it trouble on the accurate localisation and the measuring. The definition of the comptrollers ‘ behaviour in the Torahs and ordinances is expressed, so the endeavor is really easy to run in advantage of the standard cleft. Social intermediary organisations have non carry out the codification purely independently, objectively, reasonably. Richardson, Cullen and Richardson ( 1996 ) said accounting and the comptrollers ‘ behaviour is influenced by the directors. Accounting houses and other societal mediators rely to a great extent on the purposes of director. with the drive of ferocious market competition, appetency of involvement and short-action, they go against the codification of moralss for professional comptrollers, to gain much from the company that should be audited, turn a blind oculus to the deformation of accounting information or even be an component, which damaged the independency of CPA audit services, and did non truly play an function of supervising, accounting deformation information has become inevitable. Harmonizing to Morgan ( 1996 ) , in his research, we can see that accounting contributes to the procedures of societal and organisational production is a large ground that the cod ification for comptrollers is uneffective. Social environment besides influences the actions of comptrollers. Social environment means a sort of ambiance, including a traditional wonts of idea, constructs of value, mode of behaviour, and the traditional attitude and position on the economic system. Harmonizing to Maury ( Maury & A ; McCarthy 2007 ) , he thought environment that supported these accounting and ethical. With the economic development, the behaviour criterions, the working types and the societal environment has had the alteration mostly. Meanwhile, people ‘s political orientation and value is besides altering. And the codification of moralss for professional comptrollers to breed ethical behaviour is uneffective. Many jobs have risen, such as, accounting information untruthful, accounting action ‘s nonstandard. It disarrangesA the order of the accounting profession Low qualities of comptrollers result in the ineffective of the codification. Harmonizing to Lovell ( 1995 ) , moral logical thinking and moral ambiance is cardinal facet to keep the order of accounting profession. First, it ‘s hapless self-denial. Since the development of competitory societal market economic system and the impact on values, portion of the lower moral comptrollers are frequently hard to defy enticement and adhere to the rule, so that individuality, money worship, hedonism is worse and worse. Everett and Green ( 2006 ) said that the nature of accounting virtuousnesss was altering. They earn money by non entering the income and intentionally forging, changing, hiding, destructing the accounting information. Second, many accounting staffs have a thin sense of jurisprudence. Some members of the accounting profession do non analyze jurisprudence and the method of accounting criterions, cognize small about the accounting codification, or even disregard the Torahs and ordinances. They do non set histories and supervise harmonizing to the ordinances. Last, the comptrollers have a hapless sense of professional moralss. Some comptrollers normally do non pay attending to the cultivation of professional moralss, no set up a existent thought of good religion, so in practical work, when they met with struggles of national involvements, societal involvements, unit and single involvements, they can non lodge to rules and do non move harmonizing to regulations and ordinances, instead from private involvements, made a breach of professional moralss in the behavior of accounting. Internal inadvertence mechanism is non perfect and deficiency of self-discipline mechanism. Some leaders want to derive political advantage, and capital, so they require the endeavors comptrollers to work for them. Accountants are frequently out of self-defense, output to force per unit area from the leading and inactive false histories. Some internal control system is uneffective and non implemented. With deficiency of independency, the internal audit is hard to make oversight. Effective corporate administration and internal control system is the base to transport out the codification for comptrollers.DecisionCode of professional behavior for comptrollers should be a contemplation of the accounting forces ‘s ethical motives behavior. As a codification, it ‘s used to teach the accounting, to keep the behaviour of comptrollers. Code of professional behavior for comptrollers is of import in engender ethical behaviour, which can vouch the accounting informations existent and complete, and keeping the order of the activities of comptrollers, and advancing the development of societal market economic system. This article has talked about the grounds that led the ineffective of the codification of professional behavior for comptrollers. In face with these jobs, it ‘s high clip for us to take some actions to work out it, to do a good environment for accounting and breeding ethical behaviour.Undertaking 2IntroductionAccountants take the chief duty of accounting activities, pros or cons of their ethical quality and professional quality will straight impact the quality of accounting units. There are many ethical jobs about the comptrollers which have been inferred in the Question 1, such as untruth accounting information, doing unsound information, falsifying the accounting informations, hammering verifier, and even disobeying the jurisprudence. The codification of Ethics is different from the jurisprudence. Accounting jurisprudence and ordinances as a c ompulsory criterion, it requires unconditioned in conformity with the demands of legal to move. And accounting moralss from religion, character, ability and that much more profound degree of nature and to act upon and better the quality of accounting behaviour. Following, it will speak about how to do an effectual codification of moralss for professional comptrollers and the grounds. In this portion, it relates five of import grounds, and explains them individually.BodyIt ‘s a base to amend and better the codification of accounting to beef up the edifice of the moralss for professional comptrollers. Development and betterment of the codification of accounting is basically a procedure of institutional alteration and invention. This procedure must follow the rule of effectivity. It is necessary to firmly lock the long-run reform of the accounting norm system of ends, but besides give full consideration to the building of the bing accounting standard theoretical account and the c haracteristics ; it is necessary to see the key restraints of the codification in institutional agreements, but besides to see the influence of informal establishment such as accounting environment. Effective corporate administration and internal control system is of import to the execution of codification of accounting. Tisha, Emerson, Conroy and Stanley ( 2007 ) â€Å" We postulate that accounting practicians may use a legalistic model to their appraisal of the acceptableness of each sketch. † So better the system and codification is of import. Internal Control Systems provides a good internal environment the in the operation of the codification for comptrollers in the endeavor. Internal control system can be divided into internal accounting control and internal direction control, criterion, systematic, scientific internal control system enhances the monitoring attempts of accounting criterion, which can cut down the job of non obey the codification from the beginning. Internal accounting control is the key in the internal control. The procedure of constitution of sound internal accounting control itself is the execution of the codification comptrollers in the endeavor procedure ; internal accounting control in concern operations based on criterion or another is one of the basic content of the accounting criterion. The strength of full scope of accounting supervising system is a system protect for the smooth operation of the codification for the comptrollers. First, strengthen internal accounting control system which is based on the internal audit. The internal audit has uncomparable advantages compared with the external ordinance: at foremost, the internal audit staff can take part in the enterprise day-to-day concern activities, so the information accessed is more specific, elaborate and systematic than external regulators ; what ‘s more, the internal audit belongs to the internal direction of endeavors, so it can place jobs earlier and resolved internally in progress, which can gain the trust of the leaders ; at last, the internal audit is aimed to guarantee the smooth operation of the economic and better economic benefit of the company, which is in understanding with the concluding end of the accounting and leading answerability ends. Second, set uping and bettering a full scope of ex ternal monitoring system is the warrant to the smooth execution of the codification for the comptrollers. As Donaldson ( 1982 ) said, to do the codification more effectual, it should authorise more public proceedings. External supervising include civilian inadvertence of accounting houses as the behalf of investors ; the authorities supervising implemented by the fiscal sector and other relevant sections and other signifiers of extended societal monitoring such as public sentiment. Under certain conditions, a broad scope of community supervising in peculiar public sentiment can play function of inadvertence mechanisms which other machineries are hard to make. Optimization of the action of the comptrollers is besides a cardinal facet. Optimization of the comptrollers ‘ action means to optimise the entityA to accomplishing the integrating effects of group behaviour, to better efficiency and to accomplish and make of import â€Å" capable † warrant and the environment to implement the codification. Supply a good societal environment for it besides influences the actions of comptrollers. In the sentiment of Cohen, Pant and Sharp ( 1992 ) , cultural and socioeconomic factors could hinder the credence and execution of a profession ‘s international codification of behavior. Harmonizing to Stevens ( 2008 ) † Culture and effectual communicating are cardinal constituents to a codification ‘s success. † Promotion and instruction is of import. circulate consistently and explicate accountancy professional moralss through certain agencies and methods so it can make a strong ambiance of public sentiment and bit by bi t perforate into the deepnesss of people ‘s heads which can sublimate the interior universe, better the cognitive criterions, set up a moral normative value. Another step is set an illustration for presentation. Influence the ethical behaviour of accounting practicians, through promotion and instruction on the advanced theoretical accounts. Examples can be inspirational and put forward ends which can ensue in great mental strength. -e? » c ¤?aa?†cs„?†¹Ã¢â‚¬ °aa ­-c ¬Ã‚ ¦cs„?†¹?eY?Aa ­-a†¦? – ?Y?c?†¹a ­-a†¦?e? ¦c »Ã¢â‚¬  a† Ã¢â‚¬ ¦a ®? To make an excellence belongings rights environment is of import. Social environment means a sort of ambiance, including a traditional wonts of idea, constructs of value, mode of behaviour, and the traditional attitude and position on the economic system. Clear definition of belongings rights is the chief factor for comptrollers conduct accounting activities based on the codification.DecisionThe codification for comptrollers purposes to breeding ethical behaviours, and it ‘s evident that transporting out the codification for comptrollers and bettering the ethical behaviour of comptrollers are of import in the accounting activities. From recent research, it showed that the codification is non effectual, as it says in the book of Dandago ( 2003 ) . So it ‘s high clip to take some actions, such as the five actions talked above: amending and bettering the codification, effectual corporate administration and internal control system, full scope of accounting supervising system, optimisation of the action of the comptrollers and making an excellence belongings rights environment. The codification of moralss for professional comptrollers constitutes a usher, which restricts and regulates the ethical behaviour of accounting activities. It represents the accounting profession ‘s moral duty and duty to society. Strengthen the edifice of the accounting codification of moralss can do it effectual in standardising accounting behaviour.

Helpling With Organization Skills in LD Students

Helpling With Organization Skills in LD Students Helping students with the organization is important. Organization skills are worthwhile life-long skills. Some people have a knack for great organization skills and some dont. Students with learning disabilities can benefit from the following strategies to help with organization. Helping the child to develop a routine will ultimately lead to organization success. The goal of the organization is to eliminate tardiness, forgetfulness, lack of preparedness and procrastination. These habits need to be eliminated and replaced with strategies to ensure the student is utilizing good organization skills. Once again, a consistent approach that is reinforced on a regular basis will be a tremendous help. A daily agenda or timetable should be with the student at all times during the school day and every effort should be in place to ensure that its used regularly.If you have extra texts, it would benefit the student to have a copy at home.Checklists to ensure that all steps or procedures are followed should be plain view.Give the student organizers - graphic organizers, checklists, subtitles, outlines etc. that assist with written work and assignments. Sample Agenda Type List PDFBreak down all items that are to be included in assignments and provide goals to be reached and ensure that checkpoints are in place.Teach the child how to highlight pertinent information and take notes that are meaningful.Communicate regularly about progress and strategies for improvement.Make sure that you have a positive home-school connection with the support needed to ensure success.Provide verbal prompts and cues to ensure the student is prepared. For example, ask the student what needs to be done on the given night. If he answers math, ask what is needed to complete the math. Help with verbal cues often which will eventually lead to the student reflecting back on whats needed. Sometimes a checklist stating what needs to be done and whats needed to do it is very helpful. At the end of each day, the child will ensure that both are complete.Some children have great organizational skills, however, many dont. Children need to be taught that everything has a place. Organization starts at home and there are many opportunities that parents can seize to help keep a child organized. Be sure that the child knows where his belongings go. Have a spot for books, toys, writing tools, collections etc. Remind the child where things go and how to create a home for belongings that dont yet have that special place.

How To Handle Gossip About a Coworker

How To Handle Gossip About a Coworker Gossip happens. And there is always someone in every office who just can’t help but spread it. And of course, it can be fun. But it can be equally hurtful- and can damage careers- not just the person’s being gossiped about. How to take the high road? Here are a few useful strategies to keep your head above the fray.1. Set the tone.You need to be the grownup- especially if you’re a manager or supervisor and will be setting an example for your underlings. But really anyone can do this. If people start speculating wildly about company issues- or worse- gossiping about coworkers, bosses, and peers, you can be the first one to remove yourself and take a step back. This might just show them, by example, the error of their ways- without your having to say anything outright. Don’t let yourself be drawn in. If you can’t leave a conversation, try a subtle change of topic.2. Be open to negativity.People are more likely to gossip about you if you don’t s eem open to hearing their concerns or workplace issues (in the case of being a supervisor) or if you don’t seem open to constructive criticism yourself. Be as transparent as possible when you’re in a position of power. And no matter what your job title, keep the lines of communication open.3. Don’t punish the middleman.If you’re a supervisor and one employee steps forward to address an issue or bring a problem to your attention, don’t punish that person for doing so. That person’s coworkers will likely see this as a sign of your being unapproachable and unfair. Cue: gossip.4. Confront the source.Sometimes it becomes necessary to confront the gossiper, even if the gossip is about you. Most gossipers continue their chattering because they believe there are no negative consequences. But if you let them know you’re on to what they’re up to- and let them know your feelings on the matter- chances are they might stop on their own. If you have to chastise them for their behavior, make your criticism about the issue, not them personally. Don’t just say: you gossiped! that is wrong! Try instead: I’m concerned about the gossip and I’m hoping we can put an end to it. 5. Don’t be self-righteous.It’s all well and good to go high. It’s what you should be doing. But if you start to get really pompous or pious about your own good conduct in the face of rife and rampant gossip, you’re not going to make many allies. Stay casual when dealing with gossip, even when trying to be a good example. It’s not all about you, after all!

Shareholders Enjoy Growth at Dick's Sporting Goods Assignment - 30

Shareholders Enjoy Growth at Dick's Sporting Goods - Assignment Example As the paper outlines, one of the key successes of Dick's Sporting Goods is the fact that products are stocked according to a local area's seasons. This can reduce costs, which in turn the company can pass onto the customers in the form of cheaper yet high-quality products. Another reason why business has flourished is that Ed Stack has placed key emphasis on the customer experience. For any business that is struggling to establish itself in the marketplace, developing strong relationships with customers is one of the few things that can be controlled. There are so many other variables that can change depending on different factors, but being nice and courteous to customers is something that is attainable. Ed Stack has realized this and the result has been that many repeat customers have been created.  The reason why rapid growth can sometimes be a bad thing for a company is that it has not prepared to expand business operations. Few experts can predict when a company will take off , so when it does it often happens by surprise. This causes the firm to adjust its strategic goals and objectives, and sometimes it does not have long enough to accurately form these. Another reason why rapid growth is not such a good idea is that expenses tend to rise faster than revenue, creating a short-term loss. While this may not prove to be fatal to a company, it can mean that the company has to secure external financing in order to break even and doing this can strain company finances and resources. It is often the case that steady growth is better than rapid growth for the long term because the company can adapt its strategies at a pace that keeps up with the company's growth. Trying to accomplish this feat when the company is expanding rapidly is difficult to do because simple mistakes can cause damage to the company in the long term.